Medical Definition of Signal peptides

1. Additional polypeptide sequence of 25 to 30 residues at the amino-terminal or carboxy-terminal end of proteins. The signal sequence signals the cellular fate or destination of a newly synthesised protein directing it to its ultimate destination in the cell. These leaders are recognised by the signal recognition particle and bound by specific receptor sites on the outer surface of the endoplasmic reticulum. They are then transported into the cisterna of the endoplasmic reticulum and from there directed to their ultimate destination in the cell. In prokaryotes, the signal peptides attach to the plasma membrane. These signal sequences are ultimately removed by specific peptidases. (12 Dec 1998)

Lexicographical Neighbors of Signal Peptides

signal box
signal boxes
signal caller
signal crayfish
signal detection
signal detection (psychology)
signal fire
signal flag
signal level
signal light
signal node
signal peptidase
signal peptidase complex
signal peptide
signal peptide p25-subunit IV cytochrome oxidase
signal peptides (current term)
signal phrase
signal phrases
signal power
signal recognition particle
signal recognition particle receptor
signal response coupling
signal sequence
signal transduction
signal void
signaled
signaler
signalers
signalese
signaleses

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