Medical Definition of Signal recognition particle receptor

1. Receptor for the signal recognition particle (SRP) found in the membrane of the endoplasmic reticulum. Also called docking protein. Heterodimeric, both protomers having GTP binding capacity, though dissimilar binding sites. Not until the complex of SRP, ribosome, message and nascent polypeptide chain binds to the SRP receptor is the block to further chain elongation released and concurrently the SRP is released, leaving the ribosome attached to the endoplasmic reticulum membrane. Cotranslational transport of the polypeptide delivers it into the lumen of the ER. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)

Lexicographical Neighbors of Signal Recognition Particle Receptor

signal detection (psychology)
signal fire
signal flag
signal level
signal light
signal node
signal peptidase
signal peptidase complex
signal peptide
signal peptide p25-subunit IV cytochrome oxidase
signal peptides
signal phrase
signal phrases
signal power
signal recognition particle
signal recognition particle receptor (current term)
signal response coupling
signal sequence
signal transduction
signal void
signaled
signaler
signalers
signalese
signaleses
signaling
signaling device
signalings
signalisation
signalise

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