Definition of Angiotensin-converting enzyme

1. Noun. Proteolytic enzyme that converts angiotensin I into angiotensin II.




Medical Definition of Angiotensin-converting enzyme

1. This hydrolase enzyme cleaves the decapeptide angiotensin I (biologically inactive) to form active angiotensin II by angiotensin-converting enzyme which removes a dipeptide (histidylleucine) from angiotensin I. Angiotensin II causes contraction of vascular smooth muscle and thus raises blood pressure and stimulates aldosterone release from the adrenal glands. Angiotensin is finally broken down by angiotensinases. Elevations in angiotensin converting enzyme are seen sarcoidosis, histoplasmosis, alcoholic cirrhosis, asbestosis, berylliosis, diabetes, Hodgkin's disease, hyperthyroidism, amyloidosis, primary biliary cirrhosis, idiopathic pulmonary fibrosis, pulmonary embolism, scleroderma, silicosis, tuberculosis, Gaucher's disease and leprosy. The normal values are 18 to 67 U/ml over 20 years of age (people under 20 have higher levels). Drugs that inhibit ACE are used to treat hypertension and congestive heart failure. See: angiotensin-converting enzyme inhibitor Acronym: ACE (12 Aug 2000)

Angiotensin-converting Enzyme Pictures

Click the following link to bring up a new window with an automated collection of images related to the term: Angiotensin-converting Enzyme Images

Lexicographical Neighbors of Angiotensin-converting Enzyme

angiosporous
angiostasis
angiostatic
angiostatin
angiostenosis
angiostomous
angiostrongylosis
angiostrongylus
angiostrongylus cantonensis
angiotelectasia
angiotelectasis
angiotensin
angiotensin-converting enzyme (current term)
angiotensin-converting enzyme inhibitor
angiotensin-converting enzyme secretase
angiotensin-related carboxypeptidase
angiotensin I
angiotensin II
angiotensin III
angiotensin I (Phe 8-His 9) hydrolase
angiotensin amide
angiotensin converting enzyme
angiotensin converting enzyme inhibitor
angiotensin converting enzymes
angiotensin precursor
angiotensinase
angiotensinogen

Other Resources Relating to: Angiotensin-converting enzyme

Search for Angiotensin-converting enzyme on Dictionary.com!Search for Angiotensin-converting enzyme on Thesaurus.com!Search for Angiotensin-converting enzyme on Google!Search for Angiotensin-converting enzyme on Wikipedia!

Search