Definition of Angiotensinogen

1. Noun. (biochemistry) A globulin produced by the liver ¹



¹ Source: wiktionary.com

Medical Definition of Angiotensinogen

1. A family of oligopeptides ranging in size from angiotensin precursors with 14 amino acids to the active vasoconstrictor angiotensin II with 8 amino acids, or their analogs or derivatives. The amino acid content varies with the species and changes in that content produce antagonistic or inactive compounds. Angiotensinogen (renin substrate) is a 60 kD polypeptide released from the liver and cleaved in the circulation by renin to form the biologically inactive decapeptide angiotensin I. This is in turn cleaved to form active angiotensin II by Angiotensin-converting Enzyme (ACE). Angiotensin II causes contraction of vascular smooth muscle and thus raises blood pressure and stimulates aldosterone release from the adrenal glands. Angiotensin is finally broken down by angiotensinases. (12 Aug 2000)

Lexicographical Neighbors of Angiotensinogen

angiotensin
angiotensin-converting enzyme
angiotensin-converting enzyme inhibitor
angiotensin-converting enzyme secretase
angiotensin-related carboxypeptidase
angiotensin I
angiotensin II
angiotensin III
angiotensin I (Phe 8-His 9) hydrolase
angiotensin amide
angiotensin converting enzyme
angiotensin converting enzyme inhibitor
angiotensin converting enzymes
angiotensin precursor
angiotensinase
angiotensinogen (current term)
angiotensinogenase
angiotensinogenases
angiotensinogens
angiotensins
angiotomies
angiotomy
angiotonia
angiotonic
angiotonin
angiotrophic
angiya
angiyas
angklung
angklungs

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