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Medical Definition of Cold haemagglutinin disease
1. A condition associated with the presence of haemagglutinating autoantibody active in vivo but in vitro particularly or solely active in the cold; when the concentration of IgM antibody is high there may be increased serum viscosity, but clinical manifestations (due to haemagglutination) usually appear following exposure to cold; haemolysis usually is mild but may be severe, resulting in autoimmune haemolytic anaemia, cold antibody type. (05 Mar 2000)
Lexicographical Neighbors of Cold Haemagglutinin Disease
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