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Definition of MELAS
1. mela [n] - See also: mela
Medical Definition of MELAS
1. An acronym for mitochondrial myopathy, encephalopathy, lactacidosis, and stroke; an inherited disorder of the respiratory chain, either a deficiency of NADH:ubiquinone oxidoreductase (complex I of the chain) or of cytochrome c oxidase. (05 Mar 2000)